Head Clinical Pharmacology and Pharmacometrics (Executive Director – Vice President)

Head Clinical Pharmacology and Pharmacometrics (Executive Director – Vice President)

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Company Overview

At Merus, we are advancing leading-edge, targeted treatments using our pioneering multispecific antibody generating technologies, Multiclonics®, to address the unmet needs of patients with various types of cancer. Working at Merus gives you the opportunity to contribute to our mission of closing in on cancer. We care deeply about improving patients’ lives. This is why we are committed to getting this right, with a global and diverse team of highly qualified professionals. We have bold aspirations because the need is great, and the patients are waiting. Join us and make an impact. 
 

Your role:

Merus is seeking a Head of Clinical Pharmacology and Pharmacometrics to serves as the functional leader of the Translational Pharmacology, Clinical Pharmacology, and Pharmacometrics functions of the company. This position will be reporting to the VP of Clinical and Bioanalytical Sciences.

 
In this role you will:   

  • Serve as the functional leader of the Translational Pharmacology, Clinical Pharmacology, and Pharmacometrics functions of the company.
  • Be accountable for managing people, set the strategic direction of the group, and allocate resources.
  • Collaborate with other functions to integrate quantitative approaches throughout the product lifecycle, enhancing technical success and decision-making confidence. 
  • Partner with early research to provide foundational insights for optimization of key molecular attributes of mAbs and ADCs to inform prioritization from product concept to preclinical optimization.
  • Collaborate closely with clinical stage project teams to provide scientific insights that drive clinical development decisions and support regulatory submissions.

Your profile:

We are looking for a candidate with:
  • Ph.D. or equivalent degree with at least 15 years of industry experience.
  • Educational background in PKPD, pharmacometrics, chemical engineering, biomedical engineering, biostatistics, or mathematics.
  • Prior experience working with monoclonal and multispecific antibodies; experience with ADCs is preferred.
  • Demonstrated strong technical expertise in quantitative approaches to translational pharmacology, early research, and clinical development. 
  • Prior experience in using semi-/mechanistic modeling for target selection, target product profile optimization, and compound prioritization in early research.  
  • Track record in using modeling and simulation approaches to support regulatory discussions and Biologics License Application (BLA) submissions.
  • Experience in Oncology. 
  • Strong leadership skills with the ability to effectively influence cross-functional teams.
  • Strong work ethic, commitment to excellence, and openness to new ideas and feedback.

Our offer

We offer an exciting opportunity to work with some of the best and brightest in the biotech industry. As part of Merus, you’ll have the chance to collaborate with an exceptional international team of people who are passionate about what they do. To top it off, we offer a highly competitive total rewards package (benefits and compensation), training that is tailored to your individual development, and career opportunities that match your ambitions. Most importantly, you’ll have the chance to help us close in on cancer – everything you do matters at Merus.

Apply now

    Our Hiring Process

    Stage 1:

    Internal Review

    This means that we’ve received your application and are in the process of reviewing it.

    Stage 2:

    Initial Call

    We’ll set up a 15-minute phone call with our Internal Recruiter to discuss the details of this job opportunity and your own expectations of the role, as well as Merus as a company.

    Stage 3:

    1st Interview Phase

    During the 1st interview phase, we’ll set up an interview with your potential future manager. We’ll be looking to understand more about your experience, how that fits the role, and what makes you tick.

    Stage 4:

    2nd Interview Phase

    If things are still looking good, we’ll set up several short interviews with team members, peers, Management Team members (where relevant) and HR to make sure we are a good cultural fit. We do our best to plan these interviews on the same day, although on rare occasions they’ll take place on multiple days.

    Stage 5:

    Job Offer

    After positive evaluation from both sides, you will receive our job offer. Once you’ve accepted it, we will draw up the necessary paperwork. You will receive your contract within 3-5 working days and your onboarding process will start!

    Stage 6:

    Welcome

    We’re more than happy to welcome you to join Merus in our pursuit to close in on cancer!

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    Equal Employment Opportunities

    Merus is an equal employment opportunity employer that does not discriminate on the basis of actual or perceived race, color, religious creed, national origin, sex (including pregnancy, childbirth, and related medical conditions), sexual orientation, age, ancestry, disability or perceived disability, qualified handicap, gender identity, military status, veteran status, certain criminal records, genetic information or testing, HIV testing, or any other characteristic protected by applicable federal, state or local laws (each, a "Protected Characteristic"). We are dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities and general treatment during employment.

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