Senior Statistician

Senior Statistician

 Merus is seeking a Senior/Principal Biostatistician with a robust background in statistics and relevant experience in clinical trials to join our team.  To be based within our dynamic biostatistics function, you will be reporting to a Senior Director of Biostatistics. This position significantly impacts our clinical development activities, including leading the statistical aspects of clinical trials from design through to analysis, ensuring the delivery of high-quality data to support our clinical development programs. 

Your Role

As a Senior Biostatistician at Merus, you will be responsible for all statistical aspects of clinical trials, ensuring methodologies and analyses are robust and aligned with scientific objectives. Your role involves strategic collaboration with cross-functional teams and oversight of CROs to guarantee high-quality statistical deliverables.  

Areas of responsibility:   

  • Serve as the lead statistician for at least one study within our clinical development programs, offering strategic statistical input from trial design to analysis. 
  • Collaborate with cross-functional teams on study design, including sample size, randomization procedures, endpoint selection, and case report form design. 
  • Develop, oversee, and ensure the alignment of Statistical Analysis Plans (SAPs) with study objectives and regulatory compliance. 
  • Oversee CRO deliverables, ensuring the accuracy, quality, and integrity of statistical outputs, including the production of tables, listings, and figures. 
  • Foster collaborative relationships within the clinical department and with external vendors to maintain effective communication and project integrity. 
  • Provide comprehensive statistical support across all phases of clinical trial and project development, including the design of clinical study reports. 

Your Profile:

For this role, we seek a candidate with an advanced degree in statistics or equivalent, with  relevant experience pharma, biotech or CRO. You’ll bring a deep understanding of statistical principles applied to clinical research, proficiency in statistical software (e.g., SAS, R), and a proven ability to communicate complex statistical concepts clearly. Your expertise will be instrumental in driving our research forward, with strong  knowledge of statistical principles in a regulatory environment . 


  • A Master’s degree in statistics or a related field, with at least 5 years of relevant experience in clinical trial analysis.
  • Demonstrated expertise in statistical analysis within clinical or related subjects – experience in oncology is a plus.
  • Familiarity with international standards (ICH, GCP, CDISC) and clinical study regulations.
  • Proficiency in statistical software packages (e.g., SAS, R).
  • Excellent communication and interpersonal skills, with the ability to translate complex statistical concepts for non-technical audiences.
  • Strong leadership and collaboration skills, capable of working on multiple projects simultaneously and under pressure.


We offer a once-in-a-lifetime opportunity to work with some of the best and brightest in the biotech industry. As part of Merus, you’ll experience a steep learning curve from your very first day in the job. And you’ll get to interact with a great international team of people who love what they do! To top it all, we offer a competitive salary, flexible working hours, an excellent pension scheme, a company bonus and 30 days’ annual leave (based on a full-time position). Most importantly, you’ll have the chance to help us close in on cancer – everything you do matters at Merus. 

Apply now

    Our Hiring Process

    Stage 1:

    Internal Review

    This means that we’ve received your application and are in the process of reviewing it.

    Stage 2:

    Initial Call

    We’ll set up a 15-minute phone call with our Internal Recruiter to discuss the details of this job opportunity and your own expectations of the role, as well as Merus as a company.

    Stage 3:

    1st Interview Phase

    During the 1st interview phase, we’ll set up an interview with your potential future manager. We’ll be looking to understand more about your experience, how that fits the role, and what makes you tick.

    Stage 4:

    2nd Interview Phase

    If things are still looking good, we’ll set up several short interviews with team members, peers, Management Team members (where relevant) and HR to make sure we are a good cultural fit. We do our best to plan these interviews on the same day, although on rare occasions they’ll take place on multiple days.

    Stage 5:

    Job Offer

    After positive evaluation from both sides, you will receive our job offer. Once you’ve accepted it, we will draw up the necessary paperwork. You will receive your contract within 3-5 working days and your onboarding process will start!

    Stage 6:


    We’re more than happy to welcome you to join Merus in our pursuit to close in on cancer!

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