Protein Scientist (Antibody Engineer)
Protein Scientist (Antibody Engineer)
The Role
- Design, write and execute experimental studies;
- Cloning and production of large antibody panels;
- Characterization of antibodies in a range of assays including biophysical, affinity, specificity;
- Optimizing antibody sequences for developability and manufacturability;
- Delivering quality results in a timely manner;
- Propagating skills and knowledge to team members;
- Collaboration with external parties.
Your Profile:
Knowledge and expertise:
- PhD degree in molecular biology or protein chemistry with a minimum of 2 years relevant post-doctoral or industrial experience in protein production and characterization;
- Broad experience in protein chemistry, preferably including antibodies;
- Demonstrated excellence in the eukaryotic expression, purification (FPLC systems) and analysis of recombinant proteins;
- Strong knowledge and technical expertise in protein/antibody characterization including ELISA, FACS, SPR, DSF, SLS/DLS, HPLC (HIC, SEC, Ion Exchange), Mass Spectrometry;
- Experience with protein sequence/structure analysis using computational and homology modelling tools such as BioVia Discovery Studio, Pymol, or Schrödinger is preferred;
As this is a laboratory based position- preference will be given to candidates living in the Netherlands- at a commutable distance to Utrecht Science Park.
Benefits
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