Are you ready to join our fight against cancer? 
 
The team:
The Clinical Operations team is responsible for all of the clinical trials we conduct for our product candidates. Currently we have four product candidates in phase I/II studies in oncology, most of them first in class compounds.

This role is US based.

The role:

As a Senior Clinical (Trials) Manager, your main tasks and responsibilities are the following:
  • Ensure all operational trial deliverables are met according to timelines, budget, operational procedures, quality/compliance and performance standards under management of the Executive Director of Clinical Operations . This includes the management of Contract Research Organizations (CRO’s);
  • Assist in authoring protocol and related documents, development of study tools, guidelines and training materials;
  • Manage clinical study material, oversee vendors and other third parties and assist in the implementation plan(s); risk management, oversight management plans, data review processes, TMF review plans and execution, oversight monitoring plans and execution in addition to start-up, execution and close out of clinical trials
  • Global clinical trial experience in Oncology across multiple countries / regions 
  • Manage regular thorough clinical data review (at Merus and through CROs) to ensure it occurs on time, and there is timely query resolution at CROs and clinical sites  
  • Drive enrollment and recruitment activities and initiatives and provision of information to management team through site enrollment meetings, board slide preparation, management reports and dashboards 
  • Support the development, management and tracking of trial budgets with the appropriate partners internally and externally;
  • Lead internal Operations team meetings and co-lead Clinical Trial Team (CTT) meetings with the CRO 
  • Participate in the organization and logistics of various trial-related committees;
  • Manage site-related issues and procedural questions, support Executive Director & Director of Clinical Operation development of Case Report Forms (CRFs), edit checks, CRF completion guidelines, all plans etc. 
  • Assist with program level activities (e.g., development of clinical sections of regulatory documents such as Investigators’ Brochures, DSUR/PSUR, IND/NDA submission documents) and provide support, as needed, for HA and/or IRB/IEC inquiries.
  • Participation in CRA calls to assist with site follow-up, recruitment, training, protocol deviation finding resolutions, trip report review findings and overall CRA training 
  • Review of TMF and assistance with remediation of findings along with Clinical Trial Associates (CTAs) 
  • Manage site engagement and site relationships through communications and visits with clinical sites and cross-functional collaboration with Medical Affairs and Clinical Development 
  • Review of Monitoring Trip Reports and provision of timely tracking of comments and suggested remediation actions to the CRO 
  • Participation in oversight monitoring visits at clinical trial sites 

Your Profile :

When hiring new employees, we look for people who will fit in well with the collaborative, rigorous, and entrepreneurial spirit of our company – a spirit that drives us to develop advanced therapies that address unmet needs in cancer treatment.
  • Advanced (e.g. Masters) degree or equivalent education / degree in life sciences / healthcare;
  • 4 – 5 years of experience in clinical development;
  • Experience with cross-functional clinical trials, capabilities in supporting operational aspects of clinical trial related activities (planning, executing and reporting) as well as the clinical/scientific aspects;
  • Clinical Research Associate experience is strongly preferred and knowledge of how to conduct source data verification (SDV) and how to execute all types of monitoring visits – Site Initiation Visits (SIVs), Interim Monitoring Visits (IMVs) and Close Out Visits (COVs) 
  • Knowledge of GCP (Good Clinical Practice), comprehensive knowledge of clinical trial design and a good understanding of the overall drug development process; Basic knowledge of oncology, is preferred.

Our offer :

We offer an exciting opportunity to work with some of the best and brightest in the biotech industry. As part of Merus, you’ll have the chance to collaborate with an exceptional international team of people who are passionate about what they do. To top it off, we offer a highly competitive total rewards package (benefits and compensation), training that is tailored to your individual development, and career opportunities that match your ambitions. Most importantly, you’ll have the chance to help us close in on cancer – everything you do matters at Merus.

Additional Information

 
Merus is committed to fair and equitable compensation practices, aiming to provide employees with market-competitive total rewards packages.
 
The annual targeted base salary range for this role is $138,000-$208,000.
 
The targeted range reflects what Merus reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors.  The range will be reviewed regularly and is subject to change.
Central US location preferred.
 
At Merus, we are clinically advancing leading-edge, targeted treatments to address the unmet needs of patients with various types of cancer. Utilizing our proprietary technology platforms, we are developing innovative multispecific antibody therapeutics, referred to as Multiclonics®. Our therapeutic candidates engage cancer antigens and harness the power of the immune system to kill tumor cells in unique and powerful ways by utilizing our proprietary technology platform and deep expertise in oncology. We are currently developing a broad pipeline of wholly owned and licensed Biclonics® drug candidates in the clinic with compelling target combinations and unique mechanisms of action.

Medical Affairs is a new function at Merus and you have an opportunity to join us on the ground floor and build a high-functioning medical affairs organization. You will be working in an international cross-functional team, supporting the development of novel bispecific antibody therapeutics. Joining Merus means joining our pursuit to develop advanced therapies that address unmet needs in cancer treatment. The successful candidate will report to the Field Medical Director.

Your role

The Medical Science Liaison (MSL) will be responsible for engaging with Healthcare Professionals (HCPs) in their territory through appropriate high-level scientific support for education and scientific exchange.  The MSL will be a conduit for medical affairs communications and interactions for their assigned HCPs. Knowledge of oncology is required; knowledge of NGS testing and companion diagnostics is preferred.

In this role you will: 
  • Support study start-up though review of competitive trial landscape, precedent trials; leveraging contacts in medical community w/ prospective PIs, engagement and follow-up with potential sites
  • Expand company knowledge of investigational sites, both current and new, in order to build company network to include knowledge of site capabilities and past performance
  • Inform Clinical Operations when an investigator expresses an interest in becoming a site
  • Develop and execute field medical affairs plan for the assigned territory level in alignment with medical affairs strategies and tactics
  • Serve as a liaison for clinical and scientific information exchange with regional oncologists, pathologists, oncology nurses, NPs, PAs and pharmacists
  • Deliver high quality education and awareness presentations to ensure optimal patient care
  • Obtain, assimilate, organize and report field insights in a concise, clear and compliant manner
  • Provide timely, accurate, specific and balanced responses to professional requests for information in collaboration with medical communications
  • Provide complete and timely documentation of interactions and contacts 
  • Administrative reports such as expense reports and status reports completed in a timely manner
  • Provide reports, assessments and HCP insights in a clear, succinct and timely fashion
  • Maintain and continually develop scientific knowledge of the relevant competitive landscape
  • Attend and participate in all required compliance trainings
  • Follow all laws, rules, regulations, guidance documents, codes, etc. associated or attributed the pharmaceutical industry
  • Attend national, regional and local conferences and symposia in coordination with overarching company objectives
  • Follow all company policies and procedures as well as those of applicable to collaborators and institutions 

Your profile

The successful Medical Science Liaison is a proven self-starter with excellent problem-solving skills that meets the following requirement: 
  • M.D., Ph.D., Pharm.D. or NP/PA with appropriate clinical experience and scientific background
  • 2+ years’ oncology clinical experience and 1+ years’ MSL experience in pharmaceutical industry
  • Knowledge of pharmaceutical rules, regulatory law, guidelines and codes (e.g., PhRMA Code)
  • Strong collaboration skills to coordinate efforts and accomplish goals as a team
  • Demonstrate ability to develop trust and maintain integrity with internal and external partners, peers, and others
  • Ensure the attainment of individual objectives and results as well as those for the assigned team
  • Excellent interpersonal, verbal and written communication skills
  • Ability to learn new scientific and technical information quickly
  • Strong computer skills, proficiency in on-line data searches, MS Word, PowerPoint & Excel 
  • Ability to handle and prioritize multiple assignments and to meet deadlines in a fast-paced working environment
  • Travel approximately 50% (car, plane, etc.)

Our offer

We offer an exciting opportunity to work with some of the best and brightest in the biotech industry. As part of Merus, you’ll have the chance to collaborate with an exceptional international team of people who are passionate about what they do. To top it off, we offer a highly competitive total rewards package (benefits and compensation), training that is tailored to your individual development, and career opportunities that match your ambitions. Most importantly, you’ll have the chance to join us as we close in on cancer – everything you do matters at Merus.

Additional Information

 
Merus is committed to fair and equitable compensation practices, aiming to provide employees with market-competitive total rewards packages.
 
The annual targeted base salary range for this role is $156,000-$234,000.
 
The targeted range reflects what Merus reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors.  The range will be reviewed regularly and is subject to change.
The Global Head of Talent Acquisition leads the strategy and execution of all talent acquisition efforts for Merus, focusing on building a high-performing, scalable recruitment solution that supports growth across key locations, including the US and Europe. This role drives the end-to-end candidate experience, partnering closely with internal stakeholders to ensure the organization attracts, hires, and onboards top talent efficiently and effectively.

Key Responsibilities

Talent Acquisition Leadership & Strategy
  • Develop and execute a robust talent acquisition strategy aligned with the global people strategy and business growth plans.
  • Lead a high-performing TA function, leveraging both internal resources and external partners to support recruitment needs for US and European locations.
  • Build strong relationships with hiring managers and senior leaders to understand business needs and anticipate talent gaps.
  • Coach/player mindset, willing to roll up your sleeves and recruit.
  • Manage recruitment budgets, vendor partnerships, and optimize recruitment technology and processes.
Candidate Experience & Onboarding
  • Ensure a world-class candidate experience throughout the hiring lifecycle by fostering timely communication, transparency, and engagement.
  • Oversee the onboarding process to ensure new hires are set up for success, aligned with company culture, and fully integrated into their roles.
  • Continuously assess and improve onboarding programs in partnership with HR and business leaders.
 
 
 
Talent Advisor & Business Partner
  • Serve as a trusted talent advisor to business leaders, providing workforce planning insights, market intelligence, and recruitment guidance to support strategic decision-making.
  • Partner closely with HR Business Partners and senior leadership to ensure talent acquisition supports broader people strategies and business objectives.
  • Promote and enable internal mobility by identifying and advocating for existing talent opportunities within the organization to support career growth and retention.
Operational Excellence & Analytics
  • Monitor recruitment metrics and analyze data to assess effectiveness, identify bottlenecks, and drive continuous improvement.
  • Ensure compliance with employment laws and internal policies throughout the recruitment process.
  • Lead employer branding initiatives to enhance Merus’ attractiveness as an employer of choice. 

Skills, Knowledge and Expertise

We are looking for a candidate with:
  • Bachelor’s degree in Human Resources, Business, or a related field; advanced degree preferred.
  • 10+ years of progressive experience in talent acquisition leadership roles, ideally within life sciences, biotech, or similarly regulated, high-growth industries.
  • Proven success designing and executing global or multi-location TA strategies with a focus on both candidate experience and business partnership.
  • Experience managing recruitment operations leveraging both in-house and external resources.
  • Strong relationship-building skills with internal stakeholders and candidates alike.
  • Excellent communication, organizational, and analytical skills.

Our offer

We offer an exciting opportunity to work with some of the best and brightest in the biotech industry. As part of Merus, you’ll have the chance to collaborate with an exceptional international team of people who are passionate about what they do. To top it off, we offer a highly competitive total rewards package (benefits and compensation), training that is tailored to your individual development, and career opportunities that match your ambitions. Most importantly, you’ll have the chance to join us as we close in on cancer – everything you do matters at Merus.

Equal Employment Opportunities

Merus is an equal employment opportunity employer that does not discriminate on the basis of actual or perceived race, color, religious creed, national origin, sex (including pregnancy, childbirth, and related medical conditions), sexual orientation, age, ancestry, disability or perceived disability, qualified handicap, gender identity, military status, veteran status, certain criminal records, genetic information or testing, HIV testing, or any other characteristic protected by applicable federal, state or local laws (each, a "Protected Characteristic"). We are dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities and general treatment during employment.

Fraudulent Recruiting Activities

Please be cautious of scam recruitment offers claiming to be from Merus. Such scams may come from various sources, including unsolicited email using Gmail of other non-Merus email addresses or via text. These scams seek to obtain personal information or payment from victims by offering jobs that do not exist. If you have been the victim of such a scam, please report it to Internet Crime Complaint Center(IC3) | Home Page if you are living in the US or report it to the police Aangifte of melding doen | politie.nl if you live in the Netherlands.