Senior Clinical Scientist

Senior Clinical Scientist

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We are seeking a highly skilled and motivated Senior Clinical Scientist to join our team and contribute to the development and execution of global Phase 1-3 clinical studies.

The Role:

 In this role, you will be responsible for leading and overseeing critical aspects of clinical trial development and execution.
Key Responsibilities: 
  • Lead the scientific planning and execution of clinical trials, ensuring high-quality data collection and analysis.
  • Serve as the lead clinical scientist on clinical trial teams, collaborating with cross-functional teams to develop protocols, study materials, and investigator brochures.
  • Provide medical and scientific guidance during study execution, including medical monitoring, data review, and protocol deviation analysis.
  • Collaborate on safety reporting, including SAE reconciliation, safety review meetings, and regulatory submissions.
  • Participate in the development of clinical study reports, ensuring data integrity for publications and presentations.
  • Mentor and coach other clinical scientists, fostering team capabilities.
Other Responsibilities:
Protocol and Study Design:
  • Provide medical/protocol training for site-facing roles.
  • Develop clinical sections of the Site Reference Manual.
  • Create and review informed consent form (ICF) templates.
  • Support the preparation of clinical documents.
Data Review and Interpretation:
  • Provide clinical input for study setup, data analysis, and database configuration.
  • Review patient/study data and ensure accurate reporting of protocol deviations.
  • Participate in study analysis, including interim analyses and safety board management.
  • Prepare and moderate medical data review plans.
Study Medical Oversight:
  • Collaborate with study physicians for medical/scientific guidance.
  • Assist in monitoring plan development and issue resolution.
  • Provide input during vendor selection for medical/protocol issues.
Safety Management:
  • Oversee and track safety reconciliation across studies.
  • Report Serious Adverse Events (SAEs) in Safety Review Team meetings.
  • Review and approve patient narratives, CIOMS forms, and Drug Safety Update Reports (DSURs).
  • Collaborate on post-marketing commitments and ensure timely submissions.
Regulatory and Publications:
  • Lead clinical preparations for regulatory submissions and advisory meetings.
  • Review and edit clinical study reports (CSRs) and ensure data cleanliness for publications.
  • Prepare audit responses and participate in inspection readiness activities.
Clinical Program Implementation:
  • Contribute to the development of clinical development plans and target product profiles.
  • Ensure regulatory compliance and GCP adherence at the study level.
  • Coordinate with Clinical Operations to resolve study-level issues and maintain timelines.
  • Participate in the development and training of study management staff.
  • Represent Clinical Development in global process improvement initiatives.

Your Profile

The successful Clinical Scientist works well in cross-functional teams and is an excellent communicator. This will be backed up by the following:
  • Bachelor’s degree with 15+ years, Master’s degree with 12+ years, or PhD/PharmD with relevant experience in pharmaceutical clinical drug development or the medical field.
  • Strong knowledge of clinical research regulatory requirements (GCP, ICH).
  • Proven ability to manage multiple priorities with strong analytical, leadership, and problem-solving skills.
  • Oncology experience and a degree in life sciences are preferred.
  • Experience in both early and late-phase clinical studies is highly desirable.

Why Merus?

At Merus, we are committed to creating a dynamic and supportive environment where innovation thrives. As a senior leader, you will play a key role in shaping the future of our company, ensuring the safety of our patients and driving our mission forward. Join us and be part of a team that is making a difference in the lives of patients worldwide. 

Apply now

    Our Hiring Process

    Stage 1:

    Internal Review

    This means that we’ve received your application and are in the process of reviewing it.

    Stage 2:

    Initial Call

    We’ll set up a 15-minute phone call with our Internal Recruiter to discuss the details of this job opportunity and your own expectations of the role, as well as Merus as a company.

    Stage 3:

    1st Interview Phase

    During the 1st interview phase, we’ll set up an interview with your potential future manager. We’ll be looking to understand more about your experience, how that fits the role, and what makes you tick.

    Stage 4:

    2nd Interview Phase

    If things are still looking good, we’ll set up several short interviews with team members, peers, Management Team members (where relevant) and HR to make sure we are a good cultural fit. We do our best to plan these interviews on the same day, although on rare occasions they’ll take place on multiple days.

    Stage 5:

    Job Offer

    After positive evaluation from both sides, you will receive our job offer. Once you’ve accepted it, we will draw up the necessary paperwork. You will receive your contract within 3-5 working days and your onboarding process will start!

    Stage 6:

    Welcome

    We’re more than happy to welcome you to join Merus in our pursuit to close in on cancer!

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